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VT103

VT103 is an orally bioavailable TEAD auto-palmitoylation inhibitor that disrupts the YAP/TAZ-TEAD transcriptional complex. This small molecule shows potential antitumor activity and is utilized in research models of cancers such as HER2-positive breast cancer, triple-negative breast cancer, and prostate cancer.

Product Specifications

CAS Number

2290608-13-6

Product Name Alternative

YAP–TEAD, VT 103, VT103, VT-103

Field of Research

Stem Cell & Developmental Biology

Purity

98.43% (May vary between batches)

Solubility

DMSO:50 mg/mL (121.83 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (6.09 mM)

Smiles

CNS (=O) (=O) c1ccc (Nc2ccc (cc2) C (F) (F) F) c (c1) -c1cn (C) cn1

Molecular Formula

C18H17F3N4O2S

Molecular Weight

410.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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