GSK3494245
GSK3494245 (DDD01305143) is a potent, selective, and orally bioavailable inhibitor targeting the chymotrypsin-like activity of the Leishmania donovani proteasome with an IC50 of 0.16 μM. It also inhibits the human 26S proteasome (IC50=13 μM) and demonstrates utility for researching kinetoplastid parasites in both in vitro and in vivo models.
Product Specifications
CAS Number
2080410-41-7
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Purity
95.85% (May vary between batches)
Smiles
O=C (NC1=CC=C (F) C (=C1) C2=NC3=NC=C (N3C=C2) N4CCOCC4) N5CCCC5
Molecular Formula
C21H23FN6O2
Molecular Weight
410.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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