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GSK3494245

GSK3494245 (DDD01305143) is a potent, selective, and orally bioavailable inhibitor targeting the chymotrypsin-like activity of the Leishmania donovani proteasome with an IC50 of 0.16 μM. It also inhibits the human 26S proteasome (IC50=13 μM) and demonstrates utility for researching kinetoplastid parasites in both in vitro and in vivo models.

Product Specifications

CAS Number

2080410-41-7

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Purity

95.85% (May vary between batches)

Smiles

O=C (NC1=CC=C (F) C (=C1) C2=NC3=NC=C (N3C=C2) N4CCOCC4) N5CCCC5

Molecular Formula

C21H23FN6O2

Molecular Weight

410.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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