Camonsertib
Camonsertib (RP-3500) is a highly selective ATR kinase inhibitor with an IC50 of 1 nM, showing 30-fold selectivity over mTOR and >2000-fold over related kinases. It has demonstrated potent antitumor activity in preclinical studies, supporting its investigation in cancer research involving DNA damage response pathways.
Product Specifications
CAS Number
2417489-10-0
Product Name Alternative
Camonsertib, ATM, ATR, ATR inhibitor 4, RP 3500, RP3500, RP-3500
Field of Research
Molecular Biology, Signal Transduction
Purity
98.15% (May vary between batches)
Solubility
DMSO:45 mg/mL (109.63 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1.5 mg/mL (3.65 mM)
Smiles
C[C@@H]1COCCN1c1cc (c2cnn (-c3cc[nH]n3) c2n1) [C@@]1 (O) C[C@@H]2CC[C@H] (C1) O2
Molecular Formula
C21H26N6O3
Molecular Weight
410.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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