TRK-IN-19

TRK-IN-19 (Compound I-10) is a potent and selective TRK inhibitor, demonstrating low nanomolar IC50 values against both TRKA (1.1 nM) and the TRKA G595R mutant (5.3 nM) . Its activity in cellular assays supports its research utility for investigating TRK-driven oncology models in vitro and in vivo.