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AMG8788

AMG8788 is a potent, selective, and orally bioavailable antagonist of the TRPM8 ion channel, exhibiting an IC50 of 63.2 nM. This compound is a valuable research tool for investigating TRPM8's role in vivo and in vitro, particularly in areas such as cold sensation, migraine, and urological disorders.

Product Specifications

CAS Number

1159996-43-6

Field of Research

Pharmacology & Drug Discovery

Smiles

C (NC1=CC=C (F) C=C1) (=O) N2[C@@H] (C=3C (CC2) =CC=CC3) C4=CC=C (C (F) (F) F) C=C4

Molecular Formula

C23H18F4N2O

Molecular Weight

414.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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