Renin inhibitor-1
Renin inhibitor-1 (compound 26) is a potent and orally bioavailable small molecule inhibitor of renin, demonstrating low nanomolar IC50 values against both recombinant human renin and human plasma renin activity (PRA) . This compound serves as a valuable research tool for investigating the renin-angiotensin system in the context of hypertension and renal disease, applicable in both in vitro biochemical assays and in vivo pharmacological studies.
Product Specifications
CAS Number
1093082-54-2
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (N (C (=O) [C@H]1CNCCO1) C2CC2) C=3C=4C (N (CCCNC (OC) =O) C3) =CC=CC4
Molecular Formula
C22H30N4O4
Molecular Weight
414.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680460-500 1x 500 µL
CD44 Standard (156-3C11), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040304-500 1x 500 µL
CD106 / VCAM1 (B-K9), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040218-500 1x 500 µL
CD100 (Semaphorin-4D) (A8), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040806-500 1x 500 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details