NW 1028
NW 1028 is a selective small molecule inhibitor targeting the ND1L domain of VCP/p97, blocking its ATPase activity and substrate degradation. This tool compound is used in vitro and in vivo to study p97-dependent processes in cancer research, protein homeostasis, and cell cycle regulation, including mitotic spindle function.
Product Specifications
CAS Number
2749599-78-6
Field of Research
Protein Biochemistry
Smiles
C (=O) ([C@H]1N (C (=O) C=2C=C3C (=CC2) C (=O) NC (=S) N3) CCC1) N4[C@H] (C (N) =O) CCC4
Molecular Formula
C19H21N5O4S
Molecular Weight
415.47
Storage Conditions
-20°C
Notes
For research use only.
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