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NW 1028

NW 1028 is a selective small molecule inhibitor targeting the ND1L domain of VCP/p97, blocking its ATPase activity and substrate degradation. This tool compound is used in vitro and in vivo to study p97-dependent processes in cancer research, protein homeostasis, and cell cycle regulation, including mitotic spindle function.

Product Specifications

CAS Number

2749599-78-6

Field of Research

Protein Biochemistry

Smiles

C (=O) ([C@H]1N (C (=O) C=2C=C3C (=CC2) C (=O) NC (=S) N3) CCC1) N4[C@H] (C (N) =O) CCC4

Molecular Formula

C19H21N5O4S

Molecular Weight

415.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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