POLA1 inhibitor 1
Compound 12 is an orally bioavailable POLA1 inhibitor with demonstrated antitumor activity in both in vitro and in vivo studies. It shows efficacy against various tumor types and retains potency in Adaroten-resistant cell lines, making it a useful research tool for investigating DNA replication and cancer therapeutics.
Product Specifications
CAS Number
2217671-41-3
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Smiles
O\N=C\c1cc (\C=C\C (O) =O) ccc1-c1ccc (O) c (c1) C12CC3CC (CC (C3) C1) C2
Molecular Formula
C26H27NO4
Molecular Weight
417.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog