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POLA1 inhibitor 1

Compound 12 is an orally bioavailable POLA1 inhibitor with demonstrated antitumor activity in both in vitro and in vivo studies. It shows efficacy against various tumor types and retains potency in Adaroten-resistant cell lines, making it a useful research tool for investigating DNA replication and cancer therapeutics.

Product Specifications

CAS Number

2217671-41-3

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Smiles

O\N=C\c1cc (\C=C\C (O) =O) ccc1-c1ccc (O) c (c1) C12CC3CC (CC (C3) C1) C2

Molecular Formula

C26H27NO4

Molecular Weight

417.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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