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TLR7/8 antagonist 1

TLR7/8 Antagonist 1 (Compound 16c) is an imidazoquinoline-based small molecule that potently inhibits TLR7 and TLR8 signaling with IC50 values of 3.91 and 2.19 μM, respectively. This antagonist serves as a key research tool for studying TLR pathways in autoimmune, inflammatory, and oncological contexts, with applications in both in vitro and in vivo experimental models.

Product Specifications

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Molecular Formula

C24H27N5O2

Molecular Weight

417.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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