TLR7/8 antagonist 1
TLR7/8 Antagonist 1 (Compound 16c) is an imidazoquinoline-based small molecule that potently inhibits TLR7 and TLR8 signaling with IC50 values of 3.91 and 2.19 μM, respectively. This antagonist serves as a key research tool for studying TLR pathways in autoimmune, inflammatory, and oncological contexts, with applications in both in vitro and in vivo experimental models.
Product Specifications
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Molecular Formula
C24H27N5O2
Molecular Weight
417.5
Storage Conditions
-20°C
Notes
For research use only.
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