NIC-0102
NIC-0102 is an orally bioavailable proteasome inhibitor with a pIC50 of 7.55, demonstrating specific activity against NLRP3 inflammasome activation. This small molecule is a valuable research tool for investigating NLRP3-driven pathologies in both cellular and animal models of inflammatory disease.
Product Specifications
CAS Number
2806031-94-5
Field of Research
Immunology & Inflammation, Protein Biochemistry
Smiles
C (N[C@@H] (CC1=CC=CC=C1) C (N[C@@H] (CC (C) C) B (O) O) =O) (=O) C2=C (F) C=CC=C2F
Molecular Formula
C21H25BF2N2O4
Molecular Weight
418.24
Storage Conditions
-20°C
Notes
For research use only.
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