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NIC-0102

NIC-0102 is an orally bioavailable proteasome inhibitor with a pIC50 of 7.55, demonstrating specific activity against NLRP3 inflammasome activation. This small molecule is a valuable research tool for investigating NLRP3-driven pathologies in both cellular and animal models of inflammatory disease.

Product Specifications

CAS Number

2806031-94-5

Field of Research

Immunology & Inflammation, Protein Biochemistry

Smiles

C (N[C@@H] (CC1=CC=CC=C1) C (N[C@@H] (CC (C) C) B (O) O) =O) (=O) C2=C (F) C=CC=C2F

Molecular Formula

C21H25BF2N2O4

Molecular Weight

418.24

Storage Conditions

-20°C

Notes

For research use only.

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