Tubulin polymerization-IN-9

Tubulin polymerization-IN-9 is a potent tubulin polymerization inhibitor (IC50 = 1.82 μM) that induces G2/M phase arrest, apoptosis, and mitochondrial dysfunction in K562 cells. It demonstrates significant anti-tumor and anti-vascular activity, supporting its investigation in cancer research both in vitro and in vivo.