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PHGDH-IN-2

PHGDH-IN-2 is a potent, NAD+-competitive inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 5.2 μM. It suppresses the serine synthesis pathway in cells like MDA-MB-468 and inhibits the proliferation of PHGDH-dependent cancer cells, making it a useful tool for studying cancer metabolism in vitro.

Product Specifications

Field of Research

Metabolism Research

Molecular Formula

C22H20N4O3S

Molecular Weight

420.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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