PHGDH-IN-2
PHGDH-IN-2 is a potent, NAD+-competitive inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 5.2 μM. It suppresses the serine synthesis pathway in cells like MDA-MB-468 and inhibits the proliferation of PHGDH-dependent cancer cells, making it a useful tool for studying cancer metabolism in vitro.
Product Specifications
Field of Research
Metabolism Research
Molecular Formula
C22H20N4O3S
Molecular Weight
420.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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