Sirt1/2-IN-1
Sirt1/2-IN-1 is a potent inhibitor of SIRT1 and SIRT2, with additional activity against SIRT3, leading to α-tubulin hyperacetylation. It demonstrates significant anticancer effects in vitro and is a valuable chemical probe for studying sirtuin biology in cancer and aging-related research.
Product Specifications
CAS Number
2402779-21-7
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
O=C1N2C (C3=C (C=4C (S3) =CC=C (Cl) C4) N=C2SC1) C5=CC6=C (C=C5) C=CC=C6
Molecular Formula
C22H13ClN2OS2
Molecular Weight
420.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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