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Sirt1/2-IN-1

Sirt1/2-IN-1 is a potent inhibitor of SIRT1 and SIRT2, with additional activity against SIRT3, leading to α-tubulin hyperacetylation. It demonstrates significant anticancer effects in vitro and is a valuable chemical probe for studying sirtuin biology in cancer and aging-related research.

Product Specifications

CAS Number

2402779-21-7

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Smiles

O=C1N2C (C3=C (C=4C (S3) =CC=C (Cl) C4) N=C2SC1) C5=CC6=C (C=C5) C=CC=C6

Molecular Formula

C22H13ClN2OS2

Molecular Weight

420.93

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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