MARK-IN-4
MARK-IN-4 is a highly potent, nanomolar inhibitor of microtubule affinity-regulating kinase (MARK), with an IC50 of 1 nM. This compound is a valuable research tool for investigating MARK's role in tau phosphorylation and neurofibrillary tangle pathology, relevant to Alzheimer's disease studies in cellular and biochemical models.
Product Specifications
CAS Number
1990492-86-8
Field of Research
Signal Transduction
Purity
99.93% (May vary between batches)
Smiles
C (N[C@H]1[C@H] (N) CCCC1) (=O) C2=CC (C3=C4N (C=C (C=N4) C=5C=NN (C) C5) N=C3) =CS2
Molecular Formula
C21H23N7OS
Molecular Weight
421.52
Storage Conditions
-20°C
Notes
For research use only.
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