R-HP210
R-HP210 is a small molecule inhibitor of NF-κB-mediated transcription, effectively suppressing LPS-induced expression of pro-inflammatory genes like IL-1β, IL-6, and COX-2 with an IC50 of 3.80 μM. It functions as a selective glucocorticoid receptor modulator, demonstrating anti-inflammatory activity in cellular models without inducing transactivation. This profile makes it a useful research tool for studying inflammatory pathways in vitro.
Product Specifications
Field of Research
Signal Transduction
Purity
99.35% (May vary between batches)
Smiles
O=C (C1=CC=C (CN2C (NC (C=CS3) =C3C2=O) =S) C=C1) N[C@H] (C) C4=CC=CC=C4
Molecular Formula
C22H19N3O2S2
Molecular Weight
421.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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