PARP-1-IN-2
PARP-1-IN-2 is a brain-penetrant, potent PARP1 inhibitor (IC50 = 149 nM) . It demonstrates significant antiproliferative and pro-apoptotic activity against A549 lung adenocarcinoma cells in vitro, supporting its utility in oncology research for studying DNA damage response and cancer cell death mechanisms.
Product Specifications
CAS Number
684234-55-7
Product Name Alternative
PARP1
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Purity
98.82% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:0.5 mg/mL (1.18 mM) ; DMSO:9 mg/mL (21.21 mM)
Smiles
Clc1ccc (cc1) -c1nn (CC (=O) Nc2cccc (Cl) c2) c (=O) c2ccccc12
Molecular Formula
C22H15Cl2N3O2
Molecular Weight
424.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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