Enbezotinib
Enbezotinib is a potent and selective RET kinase inhibitor that blocks its autophosphorylation. It is a valuable research tool for investigating RET-driven cancers, such as non-small cell lung cancer and thyroid cancer, in both in vitro and in vivo models.
Product Specifications
CAS Number
2359649-81-1
Product Name Alternative
RET, cRET
Field of Research
Cell Biology, Signal Transduction
Purity
99.79% (May vary between batches)
Solubility
DMSO:90 mg/mL (212.05 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.78 mM)
Smiles
[H][C@]12CCC[C@@]1 ([H]) N1Cc3cc (F) cnc3O[C@@H] (C) CNC (=O) c3cnn4cc (O2) c1nc34
Molecular Formula
C21H21FN6O3
Molecular Weight
424.43
Storage Conditions
-20°C
Notes
For research use only.
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