TRK-IN-21
TRK-IN-21 is a potent and orally bioavailable pan-TRK inhibitor, effective against wild-type and multiple mutant forms (G667C, F589L, G595R) with low nanomolar IC50 values. It is a valuable chemical tool for investigating TRK-driven oncogenesis in both cellular assays and animal models of cancer.
Product Specifications
CAS Number
2429985-55-5
Smiles
N ([C@H] (C) C1=C (F) C=CC (F) =C1) C2=NC3=C (C=NN3C=C2) C4=CN (N=C4) C5CCOCC5
Molecular Formula
C22H22F2N6O
Molecular Weight
424.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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