J-1063
J-1063 is a potent and selective oral inhibitor of ALK5 (IC50: 39 nM) . It demonstrates anti-fibrotic efficacy in liver fibrosis models by reducing inflammatory infiltration, collagen deposition, and hepatocyte necrosis, making it a valuable tool for in vitro and in vivo TGF-β signaling research.
Product Specifications
CAS Number
2374772-46-8
Field of Research
Stem Cell & Developmental Biology
Smiles
C (C (NC1=CC=CC=C1) =O) N2C=C (C (=N2) C=3N=C (C) C=CC3) C4=CC=5C (S4) =CC=NC5
Molecular Formula
C24H19N5OS
Molecular Weight
425.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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