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CDK8-IN-5

CDK8-IN-5 is a potent and selective CDK8 inhibitor with an IC50 of 72 nM. It demonstrates anti-inflammatory activity, notably increasing IL-10 production by 43%, supporting its application in researching inflammatory diseases such as inflammatory bowel disease in both cellular and animal models.

Product Specifications

CAS Number

2855087-10-2

Field of Research

Cell Biology

Smiles

OC1=C2C (=CC (=C1) C3=CC=C (C (=O) N4CCNCC4) C=C3) OC (=CC2=O) C5=CC=CC=C5

Molecular Formula

C26H22N2O4

Molecular Weight

426.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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