CDK8-IN-5
CDK8-IN-5 is a potent and selective CDK8 inhibitor with an IC50 of 72 nM. It demonstrates anti-inflammatory activity, notably increasing IL-10 production by 43%, supporting its application in researching inflammatory diseases such as inflammatory bowel disease in both cellular and animal models.
Product Specifications
CAS Number
2855087-10-2
Field of Research
Cell Biology
Smiles
OC1=C2C (=CC (=C1) C3=CC=C (C (=O) N4CCNCC4) C=C3) OC (=CC2=O) C5=CC=CC=C5
Molecular Formula
C26H22N2O4
Molecular Weight
426.46
Storage Conditions
-20°C
Notes
For research use only.
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