CDK8-IN-7
CDK8-IN-7 is a highly potent and selective small molecule inhibitor of cyclin-dependent kinase 8 (CDK8), exhibiting a dissociation constant (Kd) of 3.5 nM. This compound serves as a valuable research tool for investigating CDK8 biology and its therapeutic potential in areas such as acute myeloid leukemia (AML), with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2415156-30-6
Field of Research
Cell Biology
Smiles
C[C@@]12[C@] ([C@]3 ([C@] (CC1) ([C@]4 (C) [C@@] (CC3) (C[C@H] (N (C) C) CC4) [H]) [H]) [H]) (CC=C2C=5C6=C (C=CC5) C=NC=C6) [H]
Molecular Formula
C30H40N2
Molecular Weight
428.65
Storage Conditions
-20°C
Notes
For research use only.
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