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CDK8-IN-7

CDK8-IN-7 is a highly potent and selective small molecule inhibitor of cyclin-dependent kinase 8 (CDK8), exhibiting a dissociation constant (Kd) of 3.5 nM. This compound serves as a valuable research tool for investigating CDK8 biology and its therapeutic potential in areas such as acute myeloid leukemia (AML), with utility in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2415156-30-6

Field of Research

Cell Biology

Smiles

C[C@@]12[C@] ([C@]3 ([C@] (CC1) ([C@]4 (C) [C@@] (CC3) (C[C@H] (N (C) C) CC4) [H]) [H]) [H]) (CC=C2C=5C6=C (C=CC5) C=NC=C6) [H]

Molecular Formula

C30H40N2

Molecular Weight

428.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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