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Mardepodect hydrochloride

Mardepodect HCl is a brain-penetrant, highly selective PDE10A inhibitor (IC50: 0.37 nM) . It modulates gene expression, upregulating specific growth and signaling factors while downregulating cell cycle and apoptosis genes. This compound is a valuable research tool for investigating PDE10A's role in CNS disorders in both in vitro and in vivo models.

Product Specifications

CAS Number

2070014-78-5

Product Name Alternative

PF-2545920 HCl, PF-02545920 HCl, Apoptosis, Mardepodect HCl, MP-10 HCl, PDE10A

Field of Research

Cell Biology, Metabolism Research

Purity

95.10% (May vary between batches)

Solubility

DMSO:20 mg/mL (46.63 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (5.83 mM)

Smiles

Cl.Cn1cc (c (n1) -c1ccc (OCc2ccc3ccccc3n2) cc1) -c1ccncc1

Molecular Formula

C25H21ClN4O

Molecular Weight

428.91

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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