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ALK5-IN-31

ALK5-IN-31 is a potent and selective ALK-5 inhibitor (IC50 ≤10 nM) that blocks TGF-β-mediated SMAD signaling. This compound has demonstrated efficacy in suppressing tumor growth in vivo, supporting its use as a research tool for studying cancer, fibrosis, and systemic sclerosis.

Product Specifications

CAS Number

2785430-87-5

Field of Research

Cell Biology, Stem Cell & Developmental Biology

Smiles

N (C=1C2=C (N=NC1) C (C) =CC=C2) C3=NC (NC4=CC (F) =C (C=C4) N5CCNCC5) =NC=C3

Molecular Formula

C23H23FN8

Molecular Weight

430.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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