ALK5-IN-31
ALK5-IN-31 is a potent and selective ALK-5 inhibitor (IC50 ≤10 nM) that blocks TGF-β-mediated SMAD signaling. This compound has demonstrated efficacy in suppressing tumor growth in vivo, supporting its use as a research tool for studying cancer, fibrosis, and systemic sclerosis.
Product Specifications
CAS Number
2785430-87-5
Field of Research
Cell Biology, Stem Cell & Developmental Biology
Smiles
N (C=1C2=C (N=NC1) C (C) =CC=C2) C3=NC (NC4=CC (F) =C (C=C4) N5CCNCC5) =NC=C3
Molecular Formula
C23H23FN8
Molecular Weight
430.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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