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Nav1.8-IN-2

Nav1.8-IN-2 (compound 35A) is a highly potent and selective Nav1.8 sodium channel blocker with an IC50 of 0.4 nM. This inhibitor is a valuable research tool for investigating pain mechanisms, chronic itch, and cough reflex in both in vitro electrophysiology and in vivo preclinical models.

Product Specifications

CAS Number

2756250-30-1

Field of Research

Pharmacology & Drug Discovery

Smiles

[C@@H] (NC (=O) [C@H]1OC (=O) NC1) (C2=CC (C (F) (F) F) =C (Cl) C=C2) C3=CC=C (Cl) C=C3

Molecular Formula

C18H13Cl2F3N2O3

Molecular Weight

433.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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