Nav1.8-IN-2
Nav1.8-IN-2 (compound 35A) is a highly potent and selective Nav1.8 sodium channel blocker with an IC50 of 0.4 nM. This inhibitor is a valuable research tool for investigating pain mechanisms, chronic itch, and cough reflex in both in vitro electrophysiology and in vivo preclinical models.
Product Specifications
CAS Number
2756250-30-1
Field of Research
Pharmacology & Drug Discovery
Smiles
[C@@H] (NC (=O) [C@H]1OC (=O) NC1) (C2=CC (C (F) (F) F) =C (Cl) C=C2) C3=CC=C (Cl) C=C3
Molecular Formula
C18H13Cl2F3N2O3
Molecular Weight
433.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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