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HIV-1 inhibitor-40

HIV-1 inhibitor-40 (Compound 4ab) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with an EC50 of 1.9 nM. It demonstrates in vivo efficacy against HIV-1 replication without significant acute toxicity, though it also acts as a sensitive CYP inhibitor via orexin receptor antagonism, a consideration for drug interaction studies.

Product Specifications

Field of Research

Infectious Disease & Virology, Infectious Disease & Virology; Pharmacology & Drug Discovery, Metabolism Research, Protein Biochemistry

Molecular Formula

C25H18N6O2

Molecular Weight

434.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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