6:2 Cl-PFAES

6:2 Cl-PFAES is reproductively toxic. 6:2 Cl-PFAES can cause elevated serum estradiol and vitellogenin levels in adult males and impair embryonic development in offspring[1].

Product Specifications

CAS Number

[73606-19-6]

Product Name Alternative

F-53B

UNSPSC

12352100

Hazard Statement

H301, H332, H411

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C(F)(C(F)(OC(F)(C(F)(C(F)(C(F)(C(F)(C(F)(Cl)F)F)F)F)F)F)F)F)(O[K])=O

Molecular Formula

C8ClF16KO4S

Molecular Weight

570.67

Precautions

H301, H332, H411

References & Citations

[1]Shi G, et al. Two-generational reproductive toxicity assessment of 6:2 chlorinated polyfluorinated ether sulfonate (F-53B, a novel alternative to perfluorooctane sulfonate) in zebrafish. Environ Pollut. 2018 Dec;243 (Pt B) :1517-1527.