Edecesertib
Edecesertib (GS-5718) is a potent, selective, and orally bioavailable IRAK-4 inhibitor used in rheumatoid arthritis research. It demonstrates anti-inflammatory activity and has been utilized in both in vitro cellular assays and in vivo animal models to study IRAK-4-mediated signaling pathways.
Product Specifications
CAS Number
2408839-73-4
Product Name Alternative
IRAK-4, GS5718, GS-5718, GS 5718
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
98.84% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.58 mM) ; DMSO:80 mg/mL (183.72 mM)
Smiles
N ([C@@H] (C#N) C) C=1C=C (C=2N3C (=CC2) C=C (C#N) C=N3) N=CC1C (NC[C@H] (C (C) (C) O) F) =O
Molecular Formula
C22H22FN7O2
Molecular Weight
435.45
Storage Conditions
-20°C
Notes
For research use only.
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