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CJJ300

CJJ300 is a small molecule TGF-β signaling inhibitor (IC50: 5.3 μM) that acts by disrupting the TGF-β receptor complex formation. This mechanism effectively suppresses downstream signaling, inhibiting cellular processes such as migration in vitro, making it a useful tool for fibrosis, cancer, and developmental biology research.

Product Specifications

CAS Number

1807631-83-9

Product Name Alternative

Smad, TGFb, TGF-β, TGFβ, TGF-β/Smad, TGF-b/Smad, TGFbeta/Smad, TGF-beta, TGFbeta

Field of Research

Stem Cell & Developmental Biology

Purity

99.41% (May vary between batches)

Solubility

DMSO:100 mg/mL (229.57 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (7.58 mM)

Smiles

C (NC1=CC=CC=C1) C2=C (C) C (CNC3=CC=CC=C3) =C (C) C (CNC4=CC=CC=C4) =C2C

Molecular Formula

C30H33N3

Molecular Weight

435.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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