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PARP-1/2-IN-1

PARP-1-/2-IN-1 is a highly potent dual inhibitor of PARP-1 and PARP-2 with IC50 values of 0.51 nM and 23.11 nM, respectively. This compound is a valuable chemical tool for investigating PARP biology in cancer research, including studies of DNA damage response and synthetic lethality in cellular and animal models.

Product Specifications

CAS Number

1903744-45-5

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Smiles

C (N1C=2C (C (=O) NC1=O) =CC=CC2) C3=CC (C (=O) N4C[C@@H] (CC) N (CC) CC4) =C (F) C=C3

Molecular Formula

C24H27FN4O3

Molecular Weight

438.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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