PARP-1/2-IN-1
PARP-1-/2-IN-1 is a highly potent dual inhibitor of PARP-1 and PARP-2 with IC50 values of 0.51 nM and 23.11 nM, respectively. This compound is a valuable chemical tool for investigating PARP biology in cancer research, including studies of DNA damage response and synthetic lethality in cellular and animal models.
Product Specifications
CAS Number
1903744-45-5
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
C (N1C=2C (C (=O) NC1=O) =CC=CC2) C3=CC (C (=O) N4C[C@@H] (CC) N (CC) CC4) =C (F) C=C3
Molecular Formula
C24H27FN4O3
Molecular Weight
438.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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