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A2AAR/HDAC-IN-1

A2AAR/HDAC-IN-1 (14c) is a balanced dual antagonist of the A2A adenosine receptor (Ki = 163.5 nM) and inhibitor of histone deacetylase 1 (IC50 = 145.3 nM) . This orally bioavailable compound is a research tool for investigating cancer immunotherapy and neurodegenerative diseases in both cellular and animal models.

Product Specifications

CAS Number

2767560-51-8

Field of Research

Epigenetics & Chromatin, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Smiles

C (CC1=CC=C (C (NC2=C (N) C=CC=C2) =O) C=C1) N3C=4C (=C (N=C (N) N4) C5=CC=CO5) C=N3

Molecular Formula

C24H21N7O2

Molecular Weight

439.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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