MALT1-IN-8
MALT1-IN-8 is a highly potent and selective MALT1 protease inhibitor with an IC50 of 2 nM. It demonstrates anti-proliferative activity in OCI-LY3 lymphoma cells (IC50 = 1.16 μM) and has shown efficacy in preclinical models of B-cell lymphomas, supporting its use as a chemical probe for cancer research.
Product Specifications
CAS Number
2244109-29-1
Field of Research
Immunology & Inflammation
Smiles
N (C (NC=1C=C (Cl) C (=NC1) N2N=CC=N2) =O) C3=C (C4=C (N=C3) C=CC (Cl) =C4) C5CC5
Molecular Formula
C20H15Cl2N7O
Molecular Weight
440.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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