HDAC-IN-43

HDAC-IN-43 is a potent and selective HDAC 1/3/6 inhibitor with IC50 values of 82 nM, 45 nM, and 24 nM, respectively, and exhibits weaker activity against PI3K/mTOR. This small molecule demonstrates broad-spectrum anti-proliferative effects in vitro, making it a useful chemical probe for oncology research, particularly in studying histone deacetylase roles in cancer cell growth.