HDAC-IN-43
HDAC-IN-43 is a potent and selective HDAC 1/3/6 inhibitor with IC50 values of 82 nM, 45 nM, and 24 nM, respectively, and exhibits weaker activity against PI3K/mTOR. This small molecule demonstrates broad-spectrum anti-proliferative effects in vitro, making it a useful chemical probe for oncology research, particularly in studying histone deacetylase roles in cancer cell growth.
Product Specifications
CAS Number
1809163-24-3
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
C (C) (C) N1C=2C (=C (N=C (N2) N3CCOCC3) C4=CC (OCCCC (NO) =O) =CC=C4) N=C1
Molecular Formula
C22H28N6O4
Molecular Weight
440.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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