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ATR-IN-17

ATR-IN-17 is a highly potent and selective ATR kinase inhibitor, demonstrating significant anti-proliferative activity in LoVo colorectal cancer cells with an IC50 of 1 nM. It is a valuable chemical probe for studying DNA damage response pathways in both cellular and preclinical animal models of cancer.

Product Specifications

CAS Number

2761194-15-2

Field of Research

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Smiles

C (N) (=O) C1 (CCCCC1) C2=C3C (C (=NS3) C4=NNC (C) =C4) =NC (=C2) N5[C@H] (C) COCC5

Molecular Formula

C22H28N6O2S

Molecular Weight

440.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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