ATR-IN-17
ATR-IN-17 is a highly potent and selective ATR kinase inhibitor, demonstrating significant anti-proliferative activity in LoVo colorectal cancer cells with an IC50 of 1 nM. It is a valuable chemical probe for studying DNA damage response pathways in both cellular and preclinical animal models of cancer.
Product Specifications
CAS Number
2761194-15-2
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
C (N) (=O) C1 (CCCCC1) C2=C3C (C (=NS3) C4=NNC (C) =C4) =NC (=C2) N5[C@H] (C) COCC5
Molecular Formula
C22H28N6O2S
Molecular Weight
440.56
Storage Conditions
-20°C
Notes
For research use only.
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