PPARγ phosphorylation inhibitor 1
PPARγ phosphorylation inhibitor 1 (Compound 10) is a high-affinity PPARγ ligand that potently blocks CDK5-mediated phosphorylation at Ser273 with minimal classical agonism. This mechanism makes it a valuable research tool for studying insulin sensitization in type 2 diabetes, applicable in both cellular assays and animal models of metabolic disease.
Product Specifications
CAS Number
2882975-84-8
Field of Research
Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.86% (May vary between batches)
Smiles
O=C (O) C1=NN (C (=O) C=2C=C (OC=3C=CC=CC3) C=CC12) CC4=CC=C (Cl) C (Cl) =C4
Molecular Formula
C22H14Cl2N2O4
Molecular Weight
441.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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