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PPARγ phosphorylation inhibitor 1

PPARγ phosphorylation inhibitor 1 (Compound 10) is a high-affinity PPARγ ligand that potently blocks CDK5-mediated phosphorylation at Ser273 with minimal classical agonism. This mechanism makes it a valuable research tool for studying insulin sensitization in type 2 diabetes, applicable in both cellular assays and animal models of metabolic disease.

Product Specifications

CAS Number

2882975-84-8

Field of Research

Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.86% (May vary between batches)

Smiles

O=C (O) C1=NN (C (=O) C=2C=C (OC=3C=CC=CC3) C=CC12) CC4=CC=C (Cl) C (Cl) =C4

Molecular Formula

C22H14Cl2N2O4

Molecular Weight

441.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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