Sirpiglenastat
Sirpiglenastat (DRP-104) is a prodrug of the glutamine antagonist DON, exhibiting antitumor activity through the inhibition of glutamine metabolism. It is utilized in oncology research to investigate glutamine-dependent tumor models, with studies demonstrating its immunomodulatory effects in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
2079939-05-0
Product Name Alternative
Glutaminase, DRP-104
Field of Research
Protein Biochemistry
Purity
98.01% (May vary between batches)
Solubility
DMSO:90.5 mg/mL (204.99 mM)
Smiles
C ([C@@H] (C (N[C@H] (C (OC (C) C) =O) CCC (C=[N+]=[N-]) =O) =O) NC (C) =O) C=1C=2C (NC1) =CC=CC2
Molecular Formula
C22H27N5O5
Molecular Weight
441.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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