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CD33 splicing modulator 1

Compound 1 is a small molecule modulator of CD33 (Siglec-3) RNA splicing. By altering the expression of CD33 isoforms, this tool compound is used in vitro and in vivo to investigate the role of myeloid and microglial receptors in neurodegenerative disease research, including Alzheimer's disease.

Product Specifications

Field of Research

Immunology & Inflammation

Smiles

FC1=C (C2=C3N (N=C2) C=C (C) C=N3) C=CC (C (N (C4=C (C) C=CC=N4) [C@@H]5CCCNC5) =O) =C1

Molecular Formula

C25H25FN6O

Molecular Weight

444.5

Storage Conditions

-20°C

Notes

For research use only.

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