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Microtubule inhibitor 4

Microtubule inhibitor 4 (compound 2) is a potent small molecule that disrupts microtubule polymerization. It demonstrates potent cytotoxicity against HT-29 colon cancer cells with an IC50 of 2.1 nM. This inhibitor is a valuable research tool for studying mitosis, cytoskeleton dynamics, and cancer mechanisms in both cellular and biochemical assays.

Product Specifications

CAS Number

2411962-64-4

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

C (\C1=C (C (C) (C) C) N=CN1) =C\2/C (=O) N/C (=C\C3=CC (OC4=CC=C (F) C=C4) =CC=C3) /C (=O) N2

Molecular Formula

C25H23FN4O3

Molecular Weight

446.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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